Synthesis and stereoselective evaluation of a (1R)-(?)-myrtenal-derived pseudo C2-symmetric dodecaheterocycle as a potential heterofunctional chiral auxiliary
Alvarez Hernandez, Alejandro
2018
Sánchez-Chávez, A.C., Elena Vargas-Díaz, M., Ontiveros-Rodríguez, J.C., Pérez-Estrada, S., Flores-Bernal, G.G., Mendoza-Espinosa, D., Álvarez-Hernández, A., Delgado, F., Tamariz, J., Gerardo Zepeda-Vallejo, L, Synthesis and stereoselective evaluation of a (1R)-(?)-myrtenal-derived pseudo C2-symmetric dodecaheterocycle as a potential heterofunctional chiral auxiliary. Tetrahedron Letters, 2018, 59, 4437-4441. DOI: 10.1016/j.tetlet.2018.11.012
Abstract
The synthesis and diastereoselective performance of the pseudo C2-symmetric dodecaheterocycle 3 in nucleophilic and electrophilic reactions are reported. Compound 3 proved to be a highly diastereoselective template to generate a pair of enantiomeric moieties within its structure in a programmed manner. Hence, this study describes the synthesis of a novel potential heterobifunctional chiral auxiliary.
Artículos relacionados
Aroylthioureas: new organic ionophores for heavy-metal ion selective electrodes
Preparation of N-aryl-substituted spiro-?-lactams via Staudinger cycloaddition
Furocoumarins of three species of the genus Dorstenia
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Synthesis and Structures of some Lithium and Sodium (Aminoalcoholato)hydrido Aluminates
Synthesis of new homochiral 2,3-dialkylpiperazines derived from (R)-(?)-phenylglycinol
Bis(acetylsalicylato-j2O,O00)diaquacadmium(II)
Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.